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hesim is a modular and computationally efficient R package for health economic simulation modeling and decision analysis that provides a general framework for integrating statistical analyses with economic evaluation. The package supports cohort discrete time state transition models (DTSTMs), N-state partitioned survival models (PSMs), and individual-level continuous time state transition models (CTSTMs), encompassing both Markov (time-homogeneous and time-inhomogeneous) and semi-Markov processes. It heavily utilizes Rcpp and data.table, making individual-patient simulation, probabilistic sensitivity analysis (PSA), and incorporation of patient heterogeneity fast.

Features of the current version can be summarized as follows:


# Install from CRAN:

# Install the most up to date development version from GitHub:
# install.packages("devtools")