causalCmprsk - Nonparametric and Cox-based Estimation of ATE in Competing Risks

The causalCmprsk package is designed for estimation of average treatment effects (ATE) of two static treatment regimes on time-to-event outcomes with K competing events (K can be 1). The method uses propensity scores weighting for emulation of baseline randomization. The package accompanies the paper of Charpignon, Vakulenko-Lagun, Zheng, Magdamo et al., Uncovering the links between metformin, dementia and aging using emulated trials in EHR and systems pharmacology (submitted to Nature Medicine, 2020).

The causalCmprsk package provides two main functions: fit.cox which assumes the Cox proportional hazards regression for potential outcomes, and fit.nonpar that does not make any modeling assumptions for potential outcomes.

The causalCmprsk package can be installed by

devtools::install_github("Bella2001/causalCmprsk")

The examples of how to use causalCmprsk package are here.