seqCBS: CN Profiling using Sequencing and CBS

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.

Version: 1.2
Depends: R (≥ 2.10), clue
Published: 2012-10-29
Author: Jeremy J. Shen, Nancy R. Zhang
Maintainer: Jeremy J. Shen <jeremyjshen at>
License: GPL-2
NeedsCompilation: yes
CRAN checks: seqCBS results


Reference manual: seqCBS.pdf
Package source: seqCBS_1.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: seqCBS_1.2.tgz, r-oldrel: seqCBS_1.2.tgz
OS X Mavericks binaries: r-release: seqCBS_1.2.tgz
Old sources: seqCBS archive