TEQR: Target Equivalence Range Design

The target equivalence range (TEQR) design, previously named the toxicity equivalence range design is an up-down design patterned after the modified toxicity probability interval design.The TEQR design extends the well known 3+3 design to allow for: an explicit target range for the dose limiting toxicity (DLT) rate, more subjects at the maximum tolerated dose (MTD), and specification of a too-toxic rate, which closes a dose level, In addition, the TEQR design can be implemented to target a dose based either on toxicity rate or activity rate constrained for toxicity.

Version: 5.0-0
Published: 2014-07-19
Author: M. Suzette Blanchard
Maintainer: M. Suzette Blanchard <sblanchard at coh.org>
License: GPL-2
NeedsCompilation: no
In views: ClinicalTrials, ExperimentalDesign
CRAN checks: TEQR results

Downloads:

Reference manual: TEQR.pdf
Package source: TEQR_5.0-0.tar.gz
Windows binaries: r-devel: TEQR_5.0-0.zip, r-release: TEQR_5.0-0.zip, r-oldrel: TEQR_5.0-0.zip
OS X Snow Leopard binaries: r-release: TEQR_5.0-0.tgz, r-oldrel: TEQR_5.0-0.tgz
OS X Mavericks binaries: r-release: TEQR_5.0-0.tgz
Old sources: TEQR archive