In a clinical trial with repeated measures designs, outcomes are often taken from subjects at fixed time-points. The focus of the trial may be to compare the mean outcome in two or more groups at some pre-specified time after enrollment. In the presence of missing data auxiliary assumptions are necessary to perform such comparisons. One commonly employed assumption is the missing at random assumption (MAR). The 'samon' package allows the user to perform a (parameterized) sensitivity analysis of this assumption. In particular it can be used to examine the sensitivity of tests in the difference in outcomes to violations of the MAR assumption. The sensitivity analysis can be performed under two scenarios, a) where the data exhibit a monotone missing data pattern (see the samon() function), and, b) where in addition to a monotone missing data pattern the data exhibit intermittent missing values (see the samonIM() function).

Documentation

Manual: samon.pdf
Vignette: None available.

Maintainer: Aidan McDermott <amcderm1 at jhu.edu>

Author(s): Daniel O. Scharfstein*, Aidan McDermott*

Install package and any missing dependencies by running this line in your R console:

install.packages("samon")

Depends R (>= 2.10)
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Package samon
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Version 4.0.0
Published 2017-08-15
License GPL-2
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NeedsCompilation yes
Citation
CRAN checks samon check results
Package source samon_4.0.0.tar.gz