A pipeline to analyze photographs of disk diffusion plates. This removes the need to analyze the plates themselves, and thus analysis can be done separate from the assay. Furthermore, diskImageR removes potential researcher bias, by quantitative assessment of drug resistance as the zone diameter at multiple cutoff values of growth inhibition. This method also extends the disk diffusion assay by measuring drug tolerance (in addition to drug resistance) as the fraction of the subpopulation that is able to grow above the resistance point ("FoG"), and drug sensitivity as the rate of change from no growth to full growth ("slope").

Documentation

Manual: diskImageR.pdf
Vignette: None available.

Maintainer: Aleeza Gerstein <gerst035 at umn.edu>

Author(s): Aleeza Gerstein*, Inbal Hecht*

Install package and any missing dependencies by running this line in your R console:

install.packages("diskImageR")

Depends R (>= 3.0.3)
Imports zoo, subplex, tcltk, methods
Suggests knitr
Enhances
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Package diskImageR
Materials
URL
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Version 1.0.0
Published 2016-04-03
License GPL-3
BugReports
SystemRequirements ImageJ (all OS), Xcode (Mac)
NeedsCompilation no
Citation
CRAN checks diskImageR check results
Package source diskImageR_1.0.0.tar.gz